- Case Report
- Intestinal obstruction caused by a duplication cyst of the cecum in a neonate
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Seung-woon Keum, Min-Woo Hwang, Jong-In Na, Seung-taek Yu, Dong-Baek Kang, Yeon-Kyun Oh
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Clin Exp Pediatr. 2009;52(2):261-264. Published online February 15, 2009
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Duplication cysts are rare congenital malformations, that may be detected anywhere along the alimentary tract, and they may communicate with the intestinal tract. Cystic duplication of the cecum is especially rare. About 80% of these cases are detected in the first 2 years of life as a result of an acute intestinal obstruction, which manifests as vomiting, recurrent abdominal pain,... |
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- Original Article
- Clinical characteristics of Epstein-Barr virus infection detected
by polymerase chain reaction in children less than 15 years old
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Jong-In Na, Ok Lan Kim, Do-kyoung Seoung, Seong-Taek Yoo, Chang Woo Lee, Doo-Young Choi, Yeon-Kyun Oh, Ji-Hyun Cho, Jong-Duck Kim
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Clin Exp Pediatr. 2008;51(11):1191-1197. Published online November 15, 2008
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Purpose : Previously, Epstein-Barr virus (EBV) infection was diagnosed by serological examination; currently, many EBV antigen detection methods have been developed and applied clinically for diagnosing EBV infection. To delineate the clinical characteristics of EBV infection, clinical and laboratory findings were evaluated for patients who tested positive in EBV polymerase chain reaction (PCR).
Methods : EBV PCR was conducted in 352... |
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- Platelet count and mean platelet volume in low birth weight infants (≤2,000 g) with sepsis
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Wan-soo Lee, Jin-young Cho, Seung-taek Yoo, Chang-woo Lee, Doo-young Choi, Jong-duck Kim, Yeon-kyun Oh
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Clin Exp Pediatr. 2007;50(7):643-648. Published online July 15, 2007
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Purpose : Sepsis is a common complication in Neonatal Intensive Care Units (NICU), seen especially in low birth weight (LBW) infants. A recent study showed that fungal or gram-negative sepsis is associated with a greater degree of thrombocytopenia than is seen with gram-positive sepsis. So, this study was undertaken to examine the platelet counts and platelet indices in LBW infants... |
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- Effect of Xanthine Oxidase Inhibitor on
Cerebral Hypoxia-Ischemia in Neonatal Rats
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Dae-Ho Choi, Yeon-Kyun Oh, Seung-Tak Park
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Clin Exp Pediatr. 2002;45(6):732-742. Published online June 15, 2002
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Purpose : In order to evaluate the hypoxia-ischemia(H-I) induced neurotoxicity and the protective effect of xanthine oxidase(XO) inhibitor(allopurinol), cell number, cell viability, lactate dehydrogenase(LDH), protein synthesis(PS) and protein kinase C(PKC) activity were measured in cerebral neurons and astrocytes.
Methods : Cytotoxic effect was measured by in vitro assay at 12-72 hours after H-I on cerebral neurons and astrocytes derived from 7-day... |
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- Case Report
- A Case of Mosaic Tetraploidy
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Ji-hwan Choi, Ju-a Lee, So-ra Lee, Yeon-kyun Oh, Hee-sub Rhee, Jeong-joong Kim, See-sung Choi
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Clin Exp Pediatr. 2000;43(9):1274-1278. Published online September 15, 2000
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Tetraploidy of human chromosome(92, XXYY) has been described very rarely. Liveborn infant with tetraploidy was reported in only 17 cases(complete 7 cases, mosaicism 10 cases) in the world, and no cases have been reported in Korea. The diploid-tetraploid mosaicism could arise during the early mitosis of the zygote : In one blastomeric cell, the chromosomes replicate but the cytoplasm does... |
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- Original Article
- The Effects of Glutamate Receptor Antagonists on Cultured Cerebral Cortical Neurons of Neonatal Mouse Damaged by Oxidative Stress
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Dae-ho Choi, Yeon-kyun Oh, Seung-taek Park
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Clin Exp Pediatr. 1999;42(8):1096-1103. Published online August 15, 1999
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Purpose : To evaluate neurotoxic effects induced by oxygen-radicals, which were generated by adding xanthine oxidase(XO) and hypoxanthine(HX), and protective effects of glutamate receptor antagonist such as MK-801 and 6-cyano-7-nitroquinoxaline(CNQX).
Methods : Dissociated cell cultures were prepared from cerebrum of neonatal mouse. Tissues were dissected and diced into small pieces in phosphate buffered saline and were incubated at 37℃. Isolated cells... |
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- The Protective Effect of Vitamin E and Desferrioxamine on Cultured Cerebral Neurons of Neonatal Mouse Damaged by Ischemic Condition
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So-ra Lee, Yeon-kyun Oh, Seung-taek Park
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Clin Exp Pediatr. 1999;42(10):1426-1433. Published online October 15, 1999
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Purpose : Perinatal asphyxia is an important cause of neurologic morbidity. Experiments in animal models of hypoxic-ischemic brain injury demonstrate that brain damage starts during hypoxia-ischemia. In order to evaluate the ischemic condition-induced neurotoxic effect in view of oxi- dative stress, we examined the cytotoxic effect in cultured cerebral neurons of neonatal mouse.
Methods : Dissociated cell cultures were prepared... |
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- Effect of Oxygen Radicals on Cultured Cerebral Neurons of Neonatal Mouse
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Yeon-kyun Oh, Seung-taek Park
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Clin Exp Pediatr. 1997;40(6):786-793. Published online June 15, 1997
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Purpose : In order to elucidate the neurotoxic mechanism of oxygen radicals which
are pathological factor of ischemia, we evaluated the oxidant-induced neurotoxicity and
the neuroprotective effect of antioxidant on cultured cerebral neurons derived from
neonatal mouse.
Methods : Neurotoxic effect was investigated after cultured mouse neuronal cells were
exposed to oxygen radicals which were generated enzymatically by reaction of xanthine
oxidase(XO) and hypoxanthine(HX). And also... |
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- Statistical Study on the Incidence and Mortality Rate of Low Birth Weight Infant
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Sun-ae Kang, Jae-Kag Choi, Yeon-Kyun Oh
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Clin Exp Pediatr. 1992;35(12):1690-1695. Published online December 15, 1992
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A statistical study on the icidence and mortality rate of low birth weight infant (LBW) was done on 11,406 newborns delivered at Wonkwang University Hospital during 9 years from Jan. 1,983 to Dec. 1,991.
The results were as follows,
1) The incidence of LBW was 10.2%.
2) The incidence of LBW was higher than that of other hospital delivery (p<0.005).
3) Mortality rate of... |
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